Life & Health Sciences

Clone of Testmy New Perspectives in the Treatment of Tumor Cells by Electromagnetic Radiation at Resonance Frequencies in Cellular Membrane Channels

Scientific Field Life & Health Sciences

Fellow Prof. Salvatore Magazù re

ABSTRACT

Background
The use of electromagnetic fields has been considered as adjuvant therapy for the treatment of cancer given that some clinical trials have shown
that the irradiation of cancer cells with electromagnetic fields can slow down the disease progression.
Aims:
We hypothesize that this effect could be amplified by irradiating tumor cells with electromagnetic fields having frequencies close to the natural
resonant frequencies of membrane channels in tumor cells, in order to obtain a significant change of the ion flux across tumor cell membrane
channels, inducing the largest harmful alteration in their cellular function.
Methods:
Neuronal-like cells were used as a cell model and exposed for 6 h to electromagnetic fields at different frequencies (0, 50 Hz, 900 MHz) at the
same intensity of 2 mT. The exposure system was represented by two Helmholtz coils driven by a power amplifier in current mode and an arbitrary
function generator. FTIR spectroscopy was used to evaluate the results of the exposure.
Results:
The results of this study showed that the Amide I vibration band increased in intensity with the increase of the frequency, leading us to assume that
the displacement of the cell channels α-helices depends on the frequency of the applied electromagnetic fields.
Conclusion:
This preliminary result leads us to plan future research aimed at searching for the natural frequencies of membrane channels in tumor cells using
resonant electromagnetic fields in


Testmy New Perspectives in the Treatment of Tumor Cells by Electromagnetic Radiation at Resonance Frequencies in Cellular Membrane Channels


ABSTRACT

Background: adscom
The use of electromagnetic fields has been considered as adjuvant therapy for the treatment of cancer given that some clinical trials have shown
that the irradiation of cancer cells with electromagnetic fields can slow down the disease progression.
Aims:
We hypothesize that this effect could be amplified by irradiating tumor cells with electromagnetic fields having frequencies close to the natural
resonant frequencies of membrane channels in tumor cells, in order to obtain a significant change of the ion flux across tumor cell membrane
channels, inducing the largest harmful alteration in their cellular function.
Methods:
Neuronal-like cells were used as a cell model and exposed for 6 h to electromagnetic fields at different frequencies (0, 50 Hz, 900 MHz) at the
same intensity of 2 mT. The exposure system was represented by two Helmholtz coils driven by a power amplifier in current mode and an arbitrary
function generator. FTIR spectroscopy was used to evaluate the results of the exposure.
Results:
The results of this study showed that the Amide I vibration band increased in intensity with the increase of the frequency, leading us to assume that
the displacement of the cell channels α-helices depends on the frequency of the applied electromagnetic fields.
Conclusion:
This preliminary result leads us to plan future research aimed at searching for the natural frequencies of membrane channels in tumor cells using
resonant electromagnetic fields in


Prof. Georg von Samson-Himmelstjerna

Dr Magdalena Malinowska

Dr Magdiel Pérez-Cruz

Dr Vincenzo Lauriola

From: 
INPA
In residence: 
IRD
Project title: 
Biodiversity Valorization, Property Rights and Access to Genetic Resources: Exchange of Experiences between North and South

Dr Catherine Aubertin

Dr Catherine Aubertin
Scientific Field: 
Life & Health Sciences
Laboratory: 
IRD

Prof. Nicola Fazzalari

From: 
The University of Adelaide
In residence: 
I3MTO
Project title: 
Osteocyte driven bone remodeling: from molecular to tissular processes

Prof. Irène Garcia-Gabay

From: 
Université de Genève
In residence: 
INEM
Project title: 
Role of Interleukin 1 and Inflammasome activation for the control of infection

Dr Guillaume Collet