Immuno - Neuro Modulation (INEM)

INEM studies the mechanisms involved in host-pathogen relationships, pulmonary inflammation and neurodevelopment. To do this, INEM develops and studies murine models of human diseases. Its research is also directly linked to the clinic and aims  at improving diagnosis and therapy.  

The research topics are developed along three main axes:

- Study of the role of danger signals, receptors and signalling pathways involved in host-pathogen relationships and in pulmonary inflammatory and immune responses.

- Study of the neurodevelopment of autism and study of intellectual deficits at the neurogenetic level, but also following the neurotoxic effect of pollutants.

- A cross-disciplinary project to study neuroinflammatory mechanisms in these models.

After being an International Associated Laboratory (LIA) with the University of Cape Town in South Africa in 2007-2014, INEM has established a second LIA "Lung Inflammation" with the University of Sao Paulo, Brazil in 2012, allowing the exchange of students, engineers and researchers.

INEM has been LRQA Quality Assurance certified since 2008 and ISO 9001:2015 since 2018.

Research topics:

•             Immune responses to infections and pollutants

•             Allergy, respiratory infection and immunity

•             Inflammation, danger signals, infection and pulmonary pathologies

•             Neurotoxicity and development

•             Neurogenetics of autism and mental disabilities

Equipment and technology :

•             Analysis of lung function using plethysmography non-invasive and invasive,

•             Access to TAAM animal facilities and isolators,

•             Histology and haematology,

•             Molecular and cellular biology; Multiplex,

•             Flow cytometry and fluorescence microscopy,

•             Behavioural analysis.