Induced pluripotent stem cells (iPSCs) are pluripotent cells obtained by the development of a technique of reprogrammation of somatic cells using 4 defined factors. Such spectacular feature deserved the Nobel Prize in Physiology or Medicine in 2012. iPSCs have provoked a true revolution in the fields of Biological Sciences and Medicine. Scientists started to being able to access neurons derived from somatic cells (i.e. skin fibroblasts) of patients with neurological illnesses such as Alzheimer’s and Parkinson’s and use it as models for research laboratory studies. iPSCs opened new avenues for a better understanding about human cell differentiation, and for the ex vivo development of human organs. Besides, iPSCs brought new hopes for the development of cell therapies for conditions such as blindness and liver and kidney diseases. More recently, Scientists could obtain «mini-organs» from iPSCs. These three-dimensional structures mimic human organs, allowing a unique opportunity to access whole organs affected in different pathologies. Moreover, iPSCs derived from patients with the most diverse diseases are a highly attractive tool for screenings selecting new medicines from libraries with thousands of compounds.
In this conference the most prominent experts from the iPSCs field will discuss the different applications, advantages, and caveats of the use of iPSCs in Biological Sciences and Medicine. We will cover five main themes, namely: (1) iPSCs reprogrammation and differentiation, (2) iPSCs disease models, (3) iPSCs in drug discovery, (4) iPSCs in cell therapies, and (5) organoids (or «mini-organs») derived from iPSCs.
This international conference is organised in the framework of the ARD 2020 Biopharmaceuticals Programme.
Convenors
- Dr Denis Reis de Assis, LE STUDIUM Research Fellow / ARD 2020-BIOPHARMACEUTICALS Programme
FROM: Brain Institute of PUCRS - BR
IN RESIDENCE AT: Imaging and Brain laboratory (iBrain), UMR 1253, INSERM / University of Tours - FR - Prof. Hélène Blasco,
Imaging and Brain laboratory (iBrain), UMR 1253, INSERM / University of Tours - FR
Location
CCI Touraine : 4 bis, rue Jules Favre - 37000 TOURS - FR
The event will take place at the Palais du Commerce of Tours, built between 1757 and 1759 by the Merchants of Tours for their jurisdiction and business, in the heart of the city. The Palais de Commerce is a luxurious, sober and elegant private mansion built in Bourré stones. Its western side faces the Renaissance remains of the former Beaune-Semblançay hotel, the unfortunate silversmith of François the First. Located between the Hôtel de Ville and La Loire river, the Palais de Commerce is also a stone's throw from the Museum of Fine Arts in Tours.
PRACTICAL INFORMATIONS
PRICING
(Including two lunches, a dinner and the coffee breaks)
| Private institutions | 250 EUR |
| Public institutions | 180 EUR |
| Students & PhD Scholars | 75 EUR |
| Gala dinner | 60 EUR |
