Infectiology and Public Health (ISP)

According to the «One Health» concept, the JRU ISP conducts its research from three complementary angles:

• Understanding of the protective versus pathological host response
• Deciphering how pathogens reply to the « constraint», in particular mechanisms underlying resistance to drugs
• Understanding the evolutionary mechanisms of pathogens in the environment and livestock units, and of the development at a population scale of ecosystem-related infectious processes.

Research topics:

Infectiology according to the «One Health» concept:

• Microbial infections (bacteria, virus, parasite) and protective immunity versus in­ ammation
• Virulence mechanisms of pathogens, escape to the host and resistance to drugs
• Evolution of pathogens and development of ecosystem- related infectious process

Equipment and technology:

• Biosecurity laboratories of level 2 and 3 (BSL2 and BSL3)
• Fluidigm BioMark HD (medium-hight throughput ranscriptomic)
• Flow cytometry : analysis (BD LSR Fortessa X20) and sorting (MoFo Astrios, Beckman)
• IVIS Spectrum (in vivo imaging, bioluminescence and fluorescence)