Malaria - Current status and challenges
Malaria remains a major global health issue with millions of cases annually and half a million deaths, predominantly among children under five years in sub-Saharan Africa. The disease is caused by the protozoan Plasmodium spp. and displays a spectrum of symptoms and complications which includes cerebral malaria (CM), acute respiratory distress syndrome (ARDS), and severe anemia. The severity in human infections is determined by complex host-parasite interactions.
While much progress has been made towards reducing the burden of malaria, much work remains to be done. Advances in our understanding of host-parasite and vector-parasite interactions are crucial for preventing disease progression and transmission. However, the ambitious program to eliminate malaria faces many challenges, including drug resistance, development of insecticide resistance in some anopheline mosquitoes, and difficulties in elimination of vivax malaria.
This meeting aims at discussing the development of new drug therapies, vaccine approaches and novel strategies for vector control in the malaria field. Fundamental aspects of biology, epidemiology, pathogenesis and immunity will be debated in a highly interactive forum.
Malaria, vector, immune response, malaria pathogenesis, severe malaria, experimental cerebral malaria, therapy, Plasmodium falciparum, Plasmodium vivax
- Dr Norinne Lacerda-Queiroz, LE STUDIUM / Marie Skłodowska-Curie Research Fellow.
FORMER FELLOW FROM: National Institute of Allergy and Infectious Disease (NIAID) - National Institutes of Health (NIH) - US
IN RESIDENCE AT: Experimental and Molecular Immunology and Neurogenetics (INEM) / CNRS, University of Orléans - FR
- Dr Valérie Quesniaux,
Experimental and Molecular Immunology and Neurogenetics (INEM) / CNRS, University of Orléans - FR
- Dr Carolina Barillas-Mury, National Institutes of Health (NIH) - USA
- Dr Marcus Lacerda, Instituto de Pesquisas Leônidas & Maria Deane - BR
- Dr Jean Langhorne, Francis Crick Institute - UK
- Dr Sam Wassmer, London School of Hygiene and Tropical Medicine - UK
- Dr Silvia Portugal, Heidelberg University Hospital - DE
- Dr Dominique Soldati-Favre, Teaching Medical Centre of Geneva - CH
The conference venue is unique. Located right next to the Orléans’ cathedral, the episcopal palace of Orléans, built between 1635 and 1641, locally known as the Hôtel Dupanloup, is a classical French building which served until 1905 of residence to the bishops of Orléans. Since 2014, the renewed palace hosts the International University Center for Research and Le Studium Loire Valley Institute for Advanced Studies.
Participants will be welcomed in this exceptional surrounding, blending Middle Age and Renaissance cultures with modern design and will have the opportunity to discover French cuisine and wines.