Development of Novel Luminescent Metal-Based Imaging Agents for Infectious Disease Diagnostics

LE STUDIUM Multidisciplinary Journal, 2024, 8, 61 – 62

Peggy L. Carver, PharmD¹ ; Stéphane Petoud, PhD² ; Svetlana Eliseeva, PhD² ; Vincent L. Pecoraro, PhD¹

¹ University of Michigan College of Pharmacy, Ann Arbor, MI, USA
² CNRS / Université d’Orléans, Orléans, France

Abstract

This report summarizes work conducted during a six‑month sabbatical completed in two three‑month periods during Summer 2023 and Summer 2024 as a guest fellow at Le Studium in Orléans, France. The fellowship supported an established international collaboration focused on the development of luminescent metal‑based imaging agents for infectious disease diagnostics. The primary emphasis was on fungal and mycobacterial infections, where delays in diagnosis are associated with significant morbidity and mortality. The fellow contributed clinical infectious diseases expertise, regulatory perspective, and translational guidance to ensure alignment with potential clinical application. The fellowship enabled continued research progress, international dissemination of results, and strengthening of long‑term collaborative partnerships.

Keywords

Infectious disease diagnostics, Luminescent metal complexes, Near‑infrared molecular imaging, Invasive fungal infections, Translational biomedical research
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LE STUDIUM Multidisciplinary Journal